Phagocytosis executes delayed neuronal death after focal brain ischemia

作者: J. J. Neher , J. V. Emmrich , M. Fricker , P. K. Mander , C. Thery

DOI: 10.1073/PNAS.1308679110

关键词: NeuroscienceMERTKNeuroinflammationBiologyPhagocytosisBrain ischemiaProgrammed cell deathMicrogliaIschemiaPhagoptosis

摘要: Delayed neuronal loss and brain atrophy after cerebral ischemia contribute to stroke and dementia pathology, but the mechanisms are poorly understood. Phagocytic removal of …

参考文章(57)
P. M. Hughes, D. C. Anthony, M. Ruddin, M. S. Botham, E. L. Rankine, M. Sablone, D. Baumann, A. K. Mir, V. H. Perry, Focal lesions in the rat central nervous system induced by endothelin-1. Journal of Neuropathology and Experimental Neurology. ,vol. 62, pp. 1276- 1286 ,(2003) , 10.1093/JNEN/62.12.1276
Anna Bal-Price, Jonas J. Neher, Guy C. Brown, Agnieszka Kinsner-Ovaskainen, Inflammation and Reactive Oxygen/Nitrogen Species in Glial/Neuronal Cultures Humana Press. pp. 331- 347 ,(2011) , 10.1007/978-1-61779-077-5_16
Daniel J. Hoeppner, Michael O. Hengartner, Ralf Schnabel, Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans Nature. ,vol. 412, pp. 202- 206 ,(2001) , 10.1038/35084103
Ram Gupta, Manjeet Singh, Ajay Sharma, Neuroprotective effect of antioxidants on ischaemia and reperfusion-induced cerebral injury. Pharmacological Research. ,vol. 48, pp. 209- 215 ,(2003) , 10.1016/S1043-6618(03)00102-6
Richard M. Ransohoff, Melissa A. Brown, Innate immunity in the central nervous system Journal of Clinical Investigation. ,vol. 122, pp. 1164- 1171 ,(2012) , 10.1172/JCI58644
Yi Wu, Nitu Tibrewal, Raymond B. Birge, Phosphatidylserine recognition by phagocytes: a view to a kill Trends in Cell Biology. ,vol. 16, pp. 189- 197 ,(2006) , 10.1016/J.TCB.2006.02.003
D. E. Maddox, S. Shibata, I. J. Goldstein, Stimulated macrophages express a new glycoprotein receptor reactive with Griffonia simplicifolia I-B4 isolectin Proceedings of the National Academy of Sciences of the United States of America. ,vol. 79, pp. 166- 170 ,(1982) , 10.1073/PNAS.79.1.166
K. Fuxe, N. Kurosawa, A. Cintra, Å. Hallström, M. Goiny, L. Rosén, L. F. Agnati, U. Ungerstedt, Involvement of local ischemia in endothelin-1 induced lesions of the neostriatum of the anaesthetized rat Experimental Brain Research. ,vol. 88, pp. 131- 139 ,(1992) , 10.1007/BF02259134
Ivan Ka Ho Poon, Mark Darren Hulett, Christopher R Parish, None, Molecular mechanisms of late apoptotic/necrotic cell clearance. Cell Death & Differentiation. ,vol. 17, pp. 381- 397 ,(2010) , 10.1038/CDD.2009.195
Rikinari Hanayama, Masato Tanaka, Keiko Miwa, Azusa Shinohara, Akihiro Iwamatsu, Shigekazu Nagata, Identification of a factor that links apoptotic cells to phagocytes Nature. ,vol. 417, pp. 182- 187 ,(2002) , 10.1038/417182A