Research tool: validation of floxed α7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches
作者： Caterina M. Hernandez , Ibdanelo Cortez , Zhenglin Gu , José O. Colón-Sáez , Patricia W. Lamb
DOI: 10.1113/JPHYSIOL.2014.272054
关键词: Conditional gene knockout 、 CHRNA7 、 Receptor 、 Biology 、 Nicotinic agonist 、 Neuroscience 、 Hippocampal formation 、 Glial fibrillary acidic protein 、 Cre recombinase 、 Synapsin
摘要: … Therefore we have generated mice in which the fourth exon of the α7 … conditional knockout or α7nAChR flox . We validated the chosen approach by mating α7nAChR flox with mice …
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