PROBABILITY OF OBLITERATION AND MANAGEMENT RISK FOLLOWING GAMMA KNIFE SURGERY FOR CEREBRAL AVM

摘要: In order to define the optimal treatment for an AVM patient, probability of cure and management risk following must be estimated before treatment. Here, Gamma Knife surgery has advantage over microsurgery embolization with it's reproducibility within variability individual radiation sensitivity. Based on more than 2000 treatments, we have developed models predict obliteration, radioinduced complications a post hemorrhage first two years The factors determining overall outcome are absorbed dose in target brain, volume location age clinical history patient. obliteration equals 35, 69* ln (Dmin) -39, 66 is independent. relates average 20cm3 tissue receiving most radiation, it also related patient location. Finally, increases higher larger AVM. It decreases increasing amount given, independent For retreatments, model prediction valid, but lower as compared