The Impact of CAGE Data on Understanding Macrophage Transcriptional Biology
作者： Katharine M. Irvine , David A. Hume , Kate Schroder
关键词: Macrophage 、 CSF1R gene 、 Monocyte differentiation 、 Innate immune system 、 Transcriptional regulation 、 Genetics 、 Gene regulatory network 、 Biology 、 Computational biology
摘要: This chapter demonstrates the relevance of CAGE data to studying promoter biology in depth. In particular, we report here what have learned by from obtained macrophages, which are critical cellular mediators innate immunity. Understanding transcriptional regulation and gene regulatory networks underlying basic biological mechanisms these cells is key understanding their physiological pathological roles. The knowledge methodological approaches macrophage outlined this can be applied tissues diverse systems.
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L. SPINARDI, W. WITKE, Gelsolin and diseases. Sub-cellular biochemistry. ,vol. 45, pp. 55- 69 ,(2007) , 10.1007/978-1-4020-6191-2_3
Agnieszka M. Lichanska, Catherine M. Browne, Gregory W. Henkel, Kathleen M. Murphy, Michael C. Ostrowski, Scott R. McKercher, Richard A. Maki, David A. Hume, Differentiation of the Mononuclear Phagocyte System During Mouse Embryogenesis: The Role of Transcription Factor PU.1 Blood. ,vol. 94, pp. 127- 138 ,(1999) , 10.1182/BLOOD.V94.1.127.413K07_127_138
, Antisense Transcription in the Mammalian Transcriptome Science. ,vol. 309, pp. 1564- 1566 ,(2005) , 10.1126/SCIENCE.1112009
David A. Hume, Tedjo Sasmono, S. Roy Himes, Sudarshana M. Sharma, Agnieszka Bronisz, Myrna Constantin, Michael C. Ostrowski, Ian L. Ross, The Ewing Sarcoma Protein (EWS) Binds Directly to the Proximal Elements of the Macrophage-Specific Promoter of the CSF-1 Receptor (csf1r) Gene Journal of Immunology. ,vol. 180, pp. 6733- 6742 ,(2008) , 10.4049/JIMMUNOL.180.10.6733
M J Weidemann, David Hume, F N Breen, Interactions among granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and IFN-gamma lead to enhanced proliferation of murine macrophage progenitor cells. Journal of Immunology. ,vol. 147, pp. 1542- 1547 ,(1991)
Mark W. Feinberg, Xiaobin Zhang, Christie M. Ballantyne, Zhiping Chen, Mukesh K. Jain, Karina Sulaiman, Can Shi, Daniel I. Simon, Integrin engagement regulates monocyte differentiation through the forkhead transcription factor Foxp1. Journal of Clinical Investigation. ,vol. 114, pp. 408- 418 ,(2004) , 10.1172/JCI21100
Fiona Rae, Kyra Woods, Tedjo Sasmono, Naomi Campanale, Darrin Taylor, Dmitry A. Ovchinnikov, Sean M. Grimmond, David A. Hume, Sharon D. Ricardo, Melissa H. Little, Characterisation and Trophic Functions of Murine Embryonic Macrophages Based Upon the Use of a Csf1r-EGFP Transgene Reporter Developmental Biology. ,vol. 308, pp. 232- 246 ,(2007) , 10.1016/J.YDBIO.2007.05.027
Geoffrey J. Faulkner, Alistair R.R. Forrest, Alistair M. Chalk, Kate Schroder, Yoshihide Hayashizaki, Piero Carninci, David A. Hume, Sean M. Grimmond, A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE Genomics. ,vol. 91, pp. 281- 288 ,(2008) , 10.1016/J.YGENO.2007.11.003
Constanze Bonifer, David A Hume, The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis Frontiers in Bioscience. ,vol. 13, pp. 549- 560 ,(2008) , 10.2741/2700
Rebecca Holmes, Christine Williamson, Jo Peters, Paul Denny, Christine Wells, RIKEN GER Group, A comprehensive transcript map of the mouse Gnas imprinted complex Genome Research. ,vol. 13, pp. 1410- 1415 ,(2003) , 10.1101/GR.955503