A lower baseline glomerular filtration rate predicts high mortality and newly cerebrovascular accidents in acute ischemic stroke patients.

摘要: Chronic kidney disease (CKD) is gradually recognized as an independent risk factor for cardiovascular and cardio-/cerebrovascular disease. This study aimed to examine the association of estimated glomerular filtration rate (eGFR) clinical outcomes at 3 months after onset ischemic stroke in a hospitalized Chinese population.Totally, 972 patients with acute were enrolled into this study. Modified Diet Renal Disease (MDRD) equations used calculate eGFR define CKD. The site degree stenosis examined. Patients followed-up months. Endpoint events included all-cause death newly events. multivariate logistic model was determine between renal dysfunction patients' outcomes.Of all patients, 130 (13.4%) had reduced (<60 mL/min/1.73 m), 556 normal (≥90 m). A total 694 suffered from cerebral artery stenosis, which 293 only intracranial (ICAS), 110 extracranial carotid atherosclerotic (ECAS), 301 both ICAS ECAS. <60 mL/min/1.73m higher proportion compared those relatively eGFR. Multivariate analysis revealed that baseline m increased mortality by 3.089-fold 4.067-fold. In further analysis, associated rates ECAS patients. However, found function deteriorated (odds ratio = 8.169, 95% confidence interval 2.445-14.127).A low predicted high also strong predictor