Chemical and nuclear magnetic resonance studies of 3,3-diphenyltetrahydrofuran derivatives

作者: P. S. Portoghese , D. A. Williams

DOI: 10.1002/JHET.5570060307

关键词: Pyrolytic carbonCatalytic hydrogenationEnvelope (waves)StereochemistryCis–trans isomerismNMR spectra databaseNuclear magnetic resonanceDouble bondChemistry

摘要: Pyrolytic cyclization of a- and β-methadol methiodides afforded cis trans isomers 2-ethyl-3,3-diphenyl-5-methyltetrahydrofuran, respectively. Catalytic hydrogenation 2-ethyli-dene-3,3-diphenyl-5-methyltetrahydrofuran yielded the in a 2:1 ratio. The nmr spectra these structurally related compounds have been analyzed terms half-chair conformation for 2-ethyl-5-methyl, 2-ethyl, 5-methyl derivatives. An envelope has suggested containing double bond at C-2.

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