The Alcohol Withdrawal Syndrome

作者: A McKeon , M A Frye , N. Delanty

DOI: 10.1136/JNNP.2007.128322

关键词: DeliriumPolysubstance dependencePsychiatryAlcohol withdrawal syndromeAlcohol dependenceIntensive care medicineAbstinenceMedicineAlcohol Withdrawal DeliriumAlcohol Withdrawal SeizuresDelirium tremens

摘要: The alcohol withdrawal syndrome (AWS) is a common management problem in hospital practice for neurologists, psychiatrists and general physicians alike. Although some patients have mild symptoms may even be managed the outpatient setting, others more severe or history of adverse outcomes that requires close inpatient supervision benzodiazepine therapy. Many with AWS multiple issues (withdrawal symptoms, delirium tremens, Wernicke-Korsakoff syndrome, seizures, depression, polysubstance abuse, electrolyte disturbances liver disease), which coordinated, multidisciplinary approach. complex, careful evaluation available treatments should ensure safe detoxification most patients. consists signs arising alcohol-depen- dent individuals, typically within 24-48 hours consumption their last drink. occurs intentionally those seeking abstinence, it arise unexpectedly an alcohol-dependent patient, after admission to hospital. usually mild, abrupt cessation by patient dependence lead tremens (a dysautonomic encephalopathic state) both fatal. following addressed treating doctor (fig 1): confirming diagnosis; choosing appropriate drug regimen setting withdrawal; monitoring other complications related (including Wernicke's encephalopathy (WE), phy- sical trauma depression). In this paper, we review literature on AWS, discuss our views regarding approach management.

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