Latent infection of epidermal Langerhans cells in HIV-positive individuals.
作者： L.R. Braathen , G. Ramirez , R.O.F. Kunze , C. Mork , O. Strand
DOI: 10.1016/0923-2516(91)90047-7
关键词: Staining technique 、 Virology 、 Immunology 、 Peripheral blood mononuclear cell 、 Human immunodeficiency virus (HIV) 、 Biology 、 Alkaline phosphatase 、 Langerhans cell 、 Monocyte 、 Phosphatase 、 Monoclonal antibody
摘要: Abstract Epidermal cell suspension otained fron 3 symptom-free HIV-positive individuals were cultured and marked with monoclonal antibodies for the HIV proteins p15, p24 gp120 in alkaline phosphatase anti-alkaline staining technique. For 2 individuals, cells positive after days culture, third, 4 days. Supernatant from one of cultures infected allogeneic peripheral blood mononuclear cells. We conclude that epidermal Langerhans are latent-infected able to produce release HIV.
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