In Vitro Infection of Human Epidermal Langerhans Cells with HIV

摘要: Human epidermal Langerhans cells (Lc) play an important role in antigen presentation and immunoregulation the skin (for review see ref.(1)).They carry antigens receptors which are identical to those of classical macrophages, i.e. FcIgG, C3 MHC class II HLA-D/DR (2,3),but also T-cell markers CDKT6) CD4(T4) (4–6). Remarkably, Lc exhibit 50-fold higher amounts HLA-DR than other monocyte-macrophage lineage (7).