Assessment of change of optic nerve head cupping in pediatric glaucoma using the RetCam 120.

作者: Vasudha Erraguntla , Leslie D. MacKeen , Eshetu Atenafu , Derek Stephens , J. Raymond Buncic

DOI: 10.1016/J.JAAPOS.2006.07.011

关键词: Optic diskPediatric glaucomaMagnificationClinical courseOphthalmologyPediatric ophthalmologyOptic nerveMedicineCohen's kappaContrast (vision)

摘要: Purpose To ascertain the interobserver agreement among various specialists when analyzing images of optic nerve head taken with RetCam 120 (Clarity Medical Systems, Inc., Pleasanton, CA) for assessing progression disk cupping in pediatric glaucoma. Methods Five observers compared pairs two-dimensional photographs from 64 eyes to identify whether or not changes had occurred. Observers included a glaucoma specialist, neurophthalmologist, strabismologist, ophthalmic imaging and ophthalmology fellow. Each was masked patient identity clinical course. For each patient, reviewed prior therapy at minimum 6 months following initiation therapy. Interobserver variability calculated analysis conducted influential variables. Results Poor noted between observers. No significant association obtained level variables affecting photographic quality: contrast illumination, exposure magnification, image clarity, presence fluorescein on cornea, pixelation poor resolution. Raters problems these 75.6% observations. The Kappa statistic κ = 0.29 overall proportion p 0.69, suggesting fair but moderate agreement. Conclusions Comparison photographs, performed subjectively by different perspectives, isolation information, may be reliable indicator change. In addition, variations contrast, luminance, color, pose challenges should considered sole criterion monitoring

参考文章(12)
V. R. Algazi, John L Keltner, C. A. Johnson, Computer analysis of the optic cup in glaucoma. Investigative Ophthalmology & Visual Science. ,vol. 26, pp. 1759- 1770 ,(1985)
Lichter Pr, Variability of expert observers in evaluating the optic disc. Transactions of the American Ophthalmological Society. ,vol. 74, pp. 532- 572 ,(1976)
Anne L. Coleman, Alfred Sommer, CHERYL ENGER, Harry L. Knopf, ROBERT L. STAMPER, Donald S. Minckler, Interobserver and intraobserver variability in the detection of glaucomatous progression of the optic disc. Journal of Glaucoma. ,vol. 5, pp. 384- 389 ,(1996) , 10.1097/00061198-199612000-00005
STEVEN HANSON, SOWMYA KUMARA KRISHNAN, JOHN PHILLIPS, Observer experience and Cup:Disc ratio assessment. Optometry and Vision Science. ,vol. 78, pp. 701- 705 ,(2001) , 10.1097/00006324-200110000-00009
Harry A. Quigley, The pathogenesis of reversible cupping in congenital glaucoma. American Journal of Ophthalmology. ,vol. 84, pp. 358- 370 ,(1977) , 10.1016/0002-9394(77)90680-8
SV. V. KESSING, E. GREGERSEN, The distended disc in early stages of congenital glaucoma. Acta Ophthalmologica. ,vol. 55, pp. 431- 435 ,(2009) , 10.1111/J.1755-3768.1977.TB06119.X
Alfred Sommer, Irvin Pollack, A Edward Maumenee, Optic Disc Parameters and Onset of Glaucomatous Field Loss: I. Methods and Progressive Changes in Disc Morphology Archives of Ophthalmology. ,vol. 97, pp. 1444- 1448 ,(1979) , 10.1001/ARCHOPHT.1979.01020020106002
Shiu-Chen Wu, Samuel C.M. Huang, Ching-Liang Kuo, Ken-Kuo Lin, Sue-Mei Lin, Reversal of optic disc cupping after trabeculotomy in primary congenital glaucoma. Canadian Journal of Ophthalmology-journal Canadien D Ophtalmologie. ,vol. 37, pp. 337- 341 ,(2002) , 10.1016/S0008-4182(02)80003-5
S. D. Walter, M. Eliasziw, A. Donner, Sample size and optimal designs for reliability studies Statistics in Medicine. ,vol. 17, pp. 101- 110 ,(1998) , 10.1002/(SICI)1097-0258(19980115)17:1<101::AID-SIM727>3.0.CO;2-E
ThomasS. Dietlein, PhilippC. Jacobi, G�nterK. Krieglstein, Assessment of diagnostic criteria in management of infantile glaucoma. An analysis of tonometry, optic disc cup, corneal diameter and axial length. International Ophthalmology. ,vol. 20, pp. 21- 27 ,(1997) , 10.1007/BF00212940