作者: Vasudha Erraguntla , Leslie D. MacKeen , Eshetu Atenafu , Derek Stephens , J. Raymond Buncic
DOI: 10.1016/J.JAAPOS.2006.07.011
关键词: Optic disk 、 Pediatric glaucoma 、 Magnification 、 Clinical course 、 Ophthalmology 、 Pediatric ophthalmology 、 Optic nerve 、 Medicine 、 Cohen's kappa 、 Contrast (vision)
摘要: Purpose To ascertain the interobserver agreement among various specialists when analyzing images of optic nerve head taken with RetCam 120 (Clarity Medical Systems, Inc., Pleasanton, CA) for assessing progression disk cupping in pediatric glaucoma. Methods Five observers compared pairs two-dimensional photographs from 64 eyes to identify whether or not changes had occurred. Observers included a glaucoma specialist, neurophthalmologist, strabismologist, ophthalmic imaging and ophthalmology fellow. Each was masked patient identity clinical course. For each patient, reviewed prior therapy at minimum 6 months following initiation therapy. Interobserver variability calculated analysis conducted influential variables. Results Poor noted between observers. No significant association obtained level variables affecting photographic quality: contrast illumination, exposure magnification, image clarity, presence fluorescein on cornea, pixelation poor resolution. Raters problems these 75.6% observations. The Kappa statistic κ = 0.29 overall proportion p 0.69, suggesting fair but moderate agreement. Conclusions Comparison photographs, performed subjectively by different perspectives, isolation information, may be reliable indicator change. In addition, variations contrast, luminance, color, pose challenges should considered sole criterion monitoring