Liver transplant in Budd-Chiari syndrome: a single-center experience in Saudi Arabia.

摘要: OBJECTIVES If they do not respond to other treatments, patients with Budd-Chiari syndrome are potential candidates for a liver transplant. Timing transplant is controversial; however, before systems deteriorate, early intervention in relatively stable patient may improve the outcome and survival of these patients. MATERIALS AND METHODS Six (2 women 4 men) had (1.2%) among 475 who undergone at our center between 2001 2012. Imaging modalities including duplex ultrasound, abdominal computed tomography angiography, hematologic evaluation were part routine diagnostic work-up. Although we perform mostly living-donor transplants, received from deceased donor, because there was enough evidence justify We thought that replacing caval vein might negatively influence outcome. Postoperatively, recipients started on heparin infusion triple therapy immunosuppression; only then warfarin introduced as long-term anticoagulant. RESULTS Two died, 1 uncontrollable bleeding disseminated intravascular coagulopathy, died intensive care unit after 5 months multiorgan failure sepsis. One portal thrombosis 9 transplant; needed retransplant years owing failure, secondary chronic rejection. Graft rate 75%, 66.6%. CONCLUSIONS This first article Saudi Arabia describe this subgroup syndrome. Treatment follows therapeutic algorithm should start anticoagulation end up it be considered if treatments fail.