Release of diacylglycerol-enriched vesicles from erythrocytes with increased intracellular (Ca2+)
作者： DAVID ALLAN , M. M. BILLAH , J. B. FINEAN , ROBERT H. MICHELL
DOI: 10.1038/261058A0
关键词: Calcimycin 、 Microvesicles 、 Cell membrane 、 Intracellular 、 Ionophore 、 Vesicle 、 Divalent 、 Biophysics 、 Diacylglycerol kinase 、 Chemistry
摘要: WHEN the intracellular Ca2+ concentration of human red cells was increased by treatment with A23187, a divalent cation ionophore, they changed shape from discocyte to echinocyte1–3 and 1,2-diacylglycerol content their membranes increased2–4. In these experiments it seemed that microvesicles budded off microvillus-like projections on echinocytes2,3. We have now isolated examined composition structure.
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