On the mechanism of the decarboxylative rearrangement of thiohydroxamic esters
作者： Derek H.R. Barton , David Crich , Paierre Potier
DOI: 10.1016/S0040-4039(00)98267-4
关键词: Medicinal chemistry 、 Thermal reaction 、 Deuterium 、 Chemistry 、 Photochemistry 、 Decarboxylation 、 Photochemical decomposition
摘要: Abstract The thermal and photochemical decomposition of a typical thiohydroxamic ester (mixed anhydride) doubly labelled with deuterium has shown the reaction to be radical chain process, whereas about 20% involves cage mechanism. An improved route 1-hydroxy-5-phenylthiazolin- -2-thione is reported.
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