Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells.

作者: Pierre-Louis Tharaux , Richard C. Bukoski , Paulo N. Rocha , Steven D. Crowley , Phillip Ruiz

DOI: 10.4049/JIMMUNOL.171.1.96

关键词: Cell biologyT cellRho-associated protein kinaseRho kinase inhibitorJurkat cellsCytokineBiologyT-cell receptorIL-2 receptorSignal transduction

摘要: Coordinated rearrangements of the actin-myosin cytoskeleton facilitate early and late events in T cell activation and signal transduction. As many important features of cell shape …

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