Ocular surface squamous neoplasia

作者: Graham A. Lee , Lawrence W. Hirst

DOI: 10.1016/S0039-6257(05)80054-2

关键词: Ultraviolet lightEye neoplasmConjunctival squamous cell carcinomaDysplasiaCarcinomaDifferential diagnosisMedicineConjunctival NeoplasmDermatologyPathologyCarcinoma in situ

摘要: Ocular surface squamous neoplasia presents as a spectrum from simple dysplasia to carcinoma in situ invasive cell involving the conjunctiva well cornea. It is distinct clinical entity, although it has been known by variety of different names throughout literature. Most commonly arises limbal region, occurring particularly elderly males who have lived geographic areas exposed high levels ultraviolet-B radiation. Symptoms range none severe pain and visual loss. The development preoperative diagnostic techniques, such impression cytology, are value decision making follow-up management. Simple excision with adequate margins currently best established form treatment despite trials other modalities. course this disease may be evanescent, but more frequently slowly progressive require exenteration occasionally lead death.

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