Phylogenetic Analysis of the Bifidobacterium Genus Using Glycolysis Enzyme Sequences.

摘要: Bifidobacteria are important members of the human gastrointestinal tract that promote establishment a healthy microbial consortium in gut infants. Recent studies have established Bifidobacterium genus is polymorphic phylogenetic clade, which encompasses diversity species and subspecies encode broad range proteins implicated complex non-digestible carbohydrate uptake catabolism, ranging from breast milk oligosaccharides, to plant fibers. genomic created need properly place tree. Current approaches, based on core-genome analyses come at cost intensive sequencing demanding analytical processes. Here, we propose typing method sequences glycolysis genes they encode, provide insights into diversity, typing, phylogeny this genus. We show occur broadly these genomes, machinery necessary for biochemical spine cell, robust marker. Furthermore, glycolytic sequences-based trees congruent with both classical 16S rRNA phylogeny, core genome-based strain clustering. markers can also be used adaptive evolution genus, especially regards trends toward high GC content. This streamlined may open new avenues scale, given widespread occurrence pathway bacteria, encode.