作者: Alexander Levitzki
DOI: 10.1016/B978-0-12-374145-5.00065-6
关键词: Diabetes mellitus 、 Biochemistry 、 Drug 、 Biology 、 Protein kinase B 、 Hemorrhagic shock 、 Isoquinoline 、 Pharmacology 、 Protein kinase A 、 Kinase
摘要: Novel isoquinoline derivatives which are useful as inhibitors of protein kinases for experimental, medical, and drug design purposes disclosed. Preferred compounds specific kinase B also Furthermore, pharmaceutical compositions comprising these inhibitors, methods using such treatment diagnosis cancers, diabetes, cardiovascular pathologies, hemorrhagic shock, obesity, inflammatory diseases, diseases the central nervous system, autoimmune