Compositions and methods for treatment of bdnf-related conditions

摘要: The present invention provides, among other things, methods and compositions for treating brain-derived neurotrophic factor (BDNF)-related conditions. In some embodiments, the include administering to a subject suffering form or susceptible BDNF-related condition an angiotensin (1-7) peptide, including both linear and/or cyclic peptides, functional equivalents, analogs derivatives thereof non-peptidic receptor agonist. is based, in part, on surprising discovery that peptides can stimulate production of BDNF neuronal endothelial cells.