Cell-penetrating fusion protein for regenerating or proliferating stem cell
作者： Chong-Pyoung Chung , Yoon-Jeong Park , Jue-Yeon Lee
DOI:
关键词: Cell biology 、 Cell 、 Stem cell 、 Fusion protein 、 Endothelial stem cell 、 Apoptosis 、 Biology 、 Induced stem cells
摘要: The present invention relates to a cell permeable fusion protein for strengthening regenerative potential of stem cells, and more particularly cells stimulating the differentiation inhibiting apoptosis, maintaining functionality restoring stress-inhibited cells.
lens.org 参考文章(15)
Bipin Dalmia, Gijs Rooijen, Steven Briggs, Greg Val, Peter-Bernard Heifetz, Steven Zaplachinski, Methods for the production of multimeric protein complexes, and related compositions ,(2001)
Charles A. Gersbach, Robert E. Guldberg, Andrés J. García, In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts Journal of Cellular Biochemistry. ,vol. 100, pp. 1324- 1336 ,(2007) , 10.1002/JCB.21118
Alissa Aron, Martin P. Carroll, Stephen G. Emerson, Alevtina D. Domashenko, Gwenn Danet-Desnoyers, TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells Blood. ,vol. 116, pp. 2676- 2683 ,(2010) , 10.1182/BLOOD-2010-03-273441
Woosuk Kim, Dae Won Kim, Bich Na Shin, Dae Young Yoo, Sung Min Nam, Mi Jin Kim, Jung Hoon Choi, Yeo Sung Yoon, Moo-Ho Won, Soo Young Choi, In Koo Hwang, PEP-1-frataxin significantly increases cell proliferation and neuroblast differentiation by reducing lipid peroxidation in the mouse dentate gyrus. Neurochemical Research. ,vol. 36, pp. 2452- 2458 ,(2011) , 10.1007/S11064-011-0574-3
Ji Sun Song, Hyun Hwa Cho, Byung-Joo Lee, Yong Chan Bae, Jin Sup Jung, Role of thioredoxin 1 and thioredoxin 2 on proliferation of human adipose tissue-derived mesenchymal stem cells. Stem Cells and Development. ,vol. 20, pp. 1529- 1537 ,(2011) , 10.1089/SCD.2010.0364
Eric Vivès, Priscille Brodin, Bernard Lebleu, A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. Journal of Biological Chemistry. ,vol. 272, pp. 16010- 16017 ,(1997) , 10.1074/JBC.272.25.16010
Maurice Green, Paul M. Loewenstein, Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein. Cell. ,vol. 55, pp. 1179- 1188 ,(1988) , 10.1016/0092-8674(88)90262-0
Alan D. Frankel, Carl O. Pabo, Cellular uptake of the tat protein from human immunodeficiency virus Cell. ,vol. 55, pp. 1189- 1193 ,(1988) , 10.1016/0092-8674(88)90263-2
Hyeok Yil Kwon, Won Sik Eum, Hyun Woo Jang, Jung Hoon Kang, Jiyoon Ryu, Byung Ryong Lee, Li Hua Jin, Jinseu Park, Soo Young Choi, Transduction of Cu,Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into mammalian cells FEBS Letters. ,vol. 485, pp. 163- 167 ,(2000) , 10.1016/S0014-5793(00)02215-8
Thorsten R. Doeppner, Mimount El Aanbouri, Gunnar P.H. Dietz, Jens Weise, Sönke Schwarting, Mathias Bähr, Transplantation of TAT-Bcl-xL-transduced neural precursor cells: Long-term neuroprotection after stroke Neurobiology of Disease. ,vol. 40, pp. 265- 276 ,(2010) , 10.1016/J.NBD.2010.05.033