Biosynthesized Protein-Capped Silver Nanoparticles Induce ROS-Dependent Proapoptotic Signals and Prosurvival Autophagy in Cancer Cells
作者： Leena Fageria , Vikram Pareek , R. Venkataramana Dilip , Arpit Bhargava , Sheik Saleem Pasha
关键词: Fourier transform infrared spectroscopy 、 Cell type 、 Biophysics 、 Autophagy 、 Transmission electron microscopy 、 Cytotoxic T cell 、 Stereochemistry 、 Mesenchymal stem cell 、 Cancer cell 、 Materials science 、 Silver nanoparticle
摘要: In recent years, the use of silver nanoparticles (AgNPs) in biomedical applications has shown an unprecedented boost along with simultaneous expansion rapid, high-yielding, and sustainable AgNP synthesis methods that can deliver particles well-defined characteristics. The present study demonstrates potential metal-tolerant soil fungal isolate Penicillium shearii AJP05 for protein-capped AgNPs. were characterized using standard techniques, namely, UV–visible spectroscopy, transmission electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy. anticancer activity biosynthesized AgNPs was analyzed two different cell types varied origin, example, epithelial (hepatoma) mesenchymal (osteosarcoma). biological NPs (bAgNPs) fungal-derived outer protein coat found to be more cytotoxic than bare bAgNPs or chemically synthesized (cAgNPs). Elucidation molecular mechanism revealed in...
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Sara Castiglioni, Alessandra Cazzaniga, Cristiana Perrotta, Jeanette A.M. Maier, Silver nanoparticles-induced cytotoxicity requires ERK activation in human bladder carcinoma cells. Toxicology Letters. ,vol. 237, pp. 237- 243 ,(2015) , 10.1016/J.TOXLET.2015.06.1707
Mohd Javed Akhtar, Hisham A. Alhadlaq, Sudhir Kumar, Salman A. Alrokayan, Maqusood Ahamed, Selective cancer-killing ability of metal-based nanoparticles: implications for cancer therapy Archives of Toxicology. ,vol. 89, pp. 1895- 1907 ,(2015) , 10.1007/S00204-015-1570-1
A Biederbick, H P Elsässer, H F Kern, Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. European Journal of Cell Biology. ,vol. 66, pp. 3- 14 ,(1995)
Zhaolei Zhang, Lei Zhou, Yanqing Zhou, Jinyin Liu, Xiaoyun Xing, Jun Zhong, Guoqiang Xu, Zhenhui Kang, Jian Liu, None, Mitophagy induced by nanoparticle-peptide conjugates enabling an alternative intracellular trafficking route. Biomaterials. ,vol. 65, pp. 56- 65 ,(2015) , 10.1016/J.BIOMATERIALS.2015.06.029
Su-Jae Lee, Yoo, Yoon, Kwon, Hyun, Woo, Kim, Lim, Kim, Yoon, Suh, Titanium dioxide induces apoptotic cell death through reactive oxygen species-mediated Fas upregulation and Bax activation International Journal of Nanomedicine. ,vol. 7, pp. 1203- 1214 ,(2012) , 10.2147/IJN.S28647
Navin Jain, Arpit Bhargava, Mohit Rathi, R. Venkataramana Dilip, Jitendra Panwar, Removal of Protein Capping Enhances the Antibacterial Efficiency of Biosynthesized Silver Nanoparticles. PLOS ONE. ,vol. 10, ,(2015) , 10.1371/JOURNAL.PONE.0134337
Anish Babu, Narsireddy Amreddy, Rajagopal Ramesh, Nanoparticle-based cisplatin therapy for cancer Therapeutic Delivery. ,vol. 6, pp. 115- 119 ,(2015) , 10.4155/TDE.14.109
R.M. Gengan, K. Anand, A. Phulukdaree, A. Chuturgoon, A549 lung cell line activity of biosynthesized silver nanoparticles using Albizia adianthifolia leaf. Colloids and Surfaces B: Biointerfaces. ,vol. 105, pp. 87- 91 ,(2013) , 10.1016/J.COLSURFB.2012.12.044
Zong-ming Xiu, Qing-bo Zhang, Hema L. Puppala, Vicki L. Colvin, Pedro J. J. Alvarez, Negligible Particle-Specific Antibacterial Activity of Silver Nanoparticles Nano Letters. ,vol. 12, pp. 4271- 4275 ,(2012) , 10.1021/NL301934W
Sangiliyandi Gurunathan, Kalimuthu Kalishwaralal, Ramanathan Vaidyanathan, Deepak Venkataraman, Sureshbabu Ram Kumar Pandian, Jeyaraj Muniyandi, Nellaiah Hariharan, Soo Hyun Eom, Biosynthesis, purification and characterization of silver nanoparticles using Escherichia coli. Colloids and Surfaces B: Biointerfaces. ,vol. 74, pp. 328- 335 ,(2009) , 10.1016/J.COLSURFB.2009.07.048