Three dimensional arrays for detection or quantification of nucleic acid species
作者： Snezana Drmanac , Radoje T. Drmanac
DOI:
关键词: Hybridization probe 、 Combinatorial chemistry 、 Nucleic acid 、 Substrate (chemistry) 、 Nucleic acid sequence 、 Complementary sequences 、 Biology 、 Biochemistry
摘要: The present invention provides a method for detecting target nucleic acid species including the steps of providing an array probes affixed to substrate and plurality labeled wherein each probe is selected have first sequence which complementary portion at least one second target, being adjacent portion; applying under suitable conditions hybridization sequences sequences; introducing array; hybridizing acid; affixing adjacently hybridized in array.
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