Interaction of fibroblasts and polymer surfaces: relationship between surface free energy and fibroblast spreading

作者: P. van der Valk , A. W. J. van Pelt , H. J. Busscher , H. P. de Jong , Ch. R. H. Wildevuur

DOI: 10.1002/JBM.820170508

关键词: PolymerStereochemistryFibroblastSurface energyChemistryPolarity (international relations)Cell growthDispersion (optics)Cell divisionErgBiophysics

摘要: Cell spreading and cell division rates of a transformed line mouse lung fibroblasts were studied on various polymer surfaces in the presence serum proteins. The bare surfaces, as well protein-coated characterized by their polar (gamma ps) dispersion ds) surface free energies. appeared to be dependent energy. is low when gamma ps lower than 5 erg cm-2; marked occurs higher 15 cm-2. A similar relationship was found between polarity although less pronounced for surfaces. independent rate same all tested.

参考文章(15)
M.H. Gail, Ch.W. Boone, Cell-substrate adhesivity Experimental Cell Research. ,vol. 70, pp. 33- 40 ,(1972) , 10.1016/0014-4827(72)90178-4
Yukitaka Sugimoto, Atsuyoshi Hagiwara, Cell locomotion on differently charged substrates Experimental Cell Research. ,vol. 120, pp. 245- 252 ,(1979) , 10.1016/0014-4827(79)90384-7
R. E. Baier, E. G. Shafrin, W. A. Zisman, Adhesion: Mechanisms That Assist or Impede It Science. ,vol. 162, pp. 1360- 1368 ,(1968) , 10.1126/SCIENCE.162.3860.1360
K.S. Birdi, Cell adhesion on solids and the role of surface forces Journal of Theoretical Biology. ,vol. 93, pp. 1- 5 ,(1981) , 10.1016/0022-5193(81)90052-7
Frederick Grinnell, Marian K. Feld, Adsorption characteristics of plasma fibronectin in relationship to biological activity Journal of Biomedical Materials Research. ,vol. 15, pp. 363- 381 ,(1981) , 10.1002/JBM.820150308
H.J Busscher, J Arends, Determination of the surface forces γsd and γsP from contact angle measurements on polymers and dental enamel Journal of Colloid and Interface Science. ,vol. 81, pp. 75- 79 ,(1981) , 10.1016/0021-9797(81)90303-9
S. B. CARTER, Haptotaxis and the Mechanism of Cell Motility Nature. ,vol. 213, pp. 256- 260 ,(1967) , 10.1038/213256A0
Adam Baszkin, Donald J. Lyman, The interaction of plasma proteins with polymers. I. Relationship between polymer surface energy and protein adsorption/desorption Journal of Biomedical Materials Research. ,vol. 14, pp. 393- 403 ,(1980) , 10.1002/JBM.820140406
Judah Folkman, Anne Moscona, Role of cell shape in growth control Nature. ,vol. 273, pp. 345- 349 ,(1978) , 10.1038/273345A0