HPV vaccination - a paradigm shift in public health.

摘要: BACKGROUND In 2006, the world's first quadrivalent human papillomavirus (HPV) vaccine (Gardasil) was made available to Australian public. The HPV protects against cervical cancer, abnormalities, and genital warts related types 6, 11, 16 18. General practitioners play a vital role in preventive medicine as such should have good understanding of its primary prevention cancer precancers. OBJECTIVE This article provides an overview including efficacy safety it relates approved use Australia. DISCUSSION is quadrivalent, providing protection These represent significant burden on public health they are responsible for 70% cancers, substantial proportion 90% warts. indicated females aged 9-26 years males 9-15 ideally be administered before onset sexual activity, however sexually active patients will also benefit.