Effects of temperature and flow rate on regional blood flow and metabolism during cardiopulmonary bypass

摘要: Eleven dogs were subjected to a 150-minute period of cardiopulmonary bypass that consisted high-flow, normothermic phase, hypothermic low-flow, and then rewarming phase. Regional blood flow oxygen consumption the brain, intestines, kidney, hind limb determined at baseline 10-minute intervals during bypass. Blood carotid artery, superior mesenteric renal artery declined significantly with whereas femoral increased significantly. Although total body returned values end for these regions differed somewhat from their values. We conclude is shunted skeletal muscle, particularly high pump flows. Additionally, return after not necessarily reflected regional level.