Transcranial Low-Level Infrared Laser Irradiation Ameliorates Depression Induced by Reserpine in Rats

摘要: Transcranial low-level infrared laser is a modality of therapy based on the principle photons delivered in non-invasive manner through skull for treatment some neurological conditions such as psychological disorders, traumatic brain injuries, and neurodegenerative diseases among others. In present study, effects irradiation with different radiation powers (80, 200, 400 mW, continuous wave) were investigated normal animals subjected to forced swimming test (FST). Results indicated that there are changes FST parameters irradiated laser; lowest dose provoked significant increase animal activity (swimming climbing) decrease animal’s immobility, while highest resulted complete inverse action by significantly increasing immobility decreasing respect control animals. The (80 mW) transcranial has then utilized injected chronic reserpine (0.2 mg/kg i.p. 14 days) served an model depression. Laser successfully ameliorated depression induced electrocorticography (ECoG) spectral analysis findings study emphasized beneficial healthy Additionally, it potential antidepressant low irradiation.