First Identification of Pseudomonas aeruginosa Isolates Producing a KPC-Type Carbapenem-Hydrolyzing β-Lactamase

作者: Maria Virginia Villegas , Karen Lolans , Adriana Correa , Juan Nicolas Kattan , Jaime A. Lopez

DOI: 10.1128/AAC.01405-06

关键词: ImipenemBacteriaCitrobacter freundiiCarbapenemAntibacterial agentBiologyPseudomonadalesPseudomonas aeruginosaPseudomonadaceaeMicrobiology

摘要: In Medellin, Colombia, three Pseudomonas aeruginosa isolates with high-level carbapenem resistance (MIC ≥ 256 μg/ml) and an isolate of Citrobacter freundii reduced susceptibility to imipenem produced the plasmid-mediated class A carbapenemase KPC-2. This is first report a KPC-type β-lactamase identified outside family Enterobacteriaceae.

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