Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of Klebsiella pneumoniae

作者: Hesna Yigit , Anne Marie Queenan , Gregory J. Anderson , Antonio Domenech-Sanchez , James W. Biddle

DOI: 10.1128/AAC.45.4.1151-1161.2001

关键词:

摘要: … KPC-1 hydrolyzed not only carbapenems but also penicillins, cephalosporins, and monobactams. KPC-… revealed that clavulanic acid and tazobactam inhibited KPC-1. An examination of …

参考文章(74)
David M. Livermore, Bacterial Resistance to Carbapenems Antimicrobial Resistance. ,vol. 390, pp. 25- 47 ,(1995) , 10.1007/978-1-4757-9203-4_3
S Pollitt, H Zalkin, Role of primary structure and disulfide bond formation in beta-lactamase secretion. Journal of Bacteriology. ,vol. 153, pp. 27- 32 ,(1983) , 10.1128/JB.153.1.27-32.1983
C de Champs, C Henquell, D Guelon, D Sirot, N Gazuy, J Sirot, Clinical and bacteriological study of nosocomial infections due to Enterobacter aerogenes resistant to imipenem. Journal of Clinical Microbiology. ,vol. 31, pp. 123- 127 ,(1993) , 10.1128/JCM.31.1.123-127.1993
Erika Bruck, National Committee for Clinical Laboratory Standards. Pediatrics. ,vol. 65, pp. 187- 188 ,(1980)
Paul D. Stapleton, Kevin P. Shannon, Gary L. French, Carbapenem Resistance in Escherichia coli Associated with Plasmid-Determined CMY-4 β-Lactamase Production and Loss of an Outer Membrane Protein Antimicrobial Agents and Chemotherapy. ,vol. 43, pp. 1206- 1210 ,(1999) , 10.1128/AAC.43.5.1206
B Fournier, P H Roy, P H Lagrange, A Philippon, Chromosomal beta-lactamase genes of Klebsiella oxytoca are divided into two main groups, blaOXY-1 and blaOXY-2 Antimicrobial Agents and Chemotherapy. ,vol. 40, pp. 454- 459 ,(1996) , 10.1128/AAC.40.2.454
R P Ambler, A F W Coulson, J M Frère, J M Ghuysen, B Joris, M Forsman, R C Levesque, G Tiraby, S G Waley, A standard numbering scheme for the class A beta-lactamases. Biochemical Journal. ,vol. 276, pp. 269- 270 ,(1991) , 10.1042/BJ2760269
T R Walsh, A P MacGowan, P M Bennett, Sequence analysis and enzyme kinetics of the L2 serine beta-lactamase from Stenotrophomonas maltophilia. Antimicrobial Agents and Chemotherapy. ,vol. 41, pp. 1460- 1464 ,(1997) , 10.1128/AAC.41.7.1460
D A Portnoy, H Wolf-Watz, I Bolin, A B Beeder, S Falkow, Characterization of common virulence plasmids in Yersinia species and their role in the expression of outer membrane proteins. Infection and Immunity. ,vol. 43, pp. 108- 114 ,(1984) , 10.1128/IAI.43.1.108-114.1984