Construction of receiver operating characteristic curves when disease verification is subject to selection bias

作者: Robert Gray , Colin B. Begg , Robert A. Greenes

DOI: 10.1177/0272989X8400400204

关键词: PopulationStatisticsDisease statusComputed tomographyProbability distributionSelection biasReceiver operating characteristicDiagnostic testComputer scienceSample (statistics)

摘要: The estimates of ROC curves, which are frequently used in the assessment diagnostic tests, may be biased if sample is restricted to subjects whose disease status has been definitively verified. A method provide an unbiased estimate curve under these conditions proposed. new requires information on probability distribution test results population from verified drawn. It illustrated using data a study computed tomography for fever uncertain origin.

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