Antidiabetic drugs and risk of cancer

摘要: Antidiabetic drugs are an important group of medications used worldwide. They differ from each other in the mechanisms lowering blood glucose as well adverse effects that may affect course treatment and its efficacy. In recent years, new have been discovered order to improve maintenance proper level reduce unwanted these drugs. Their growing administration is related increasing incidence diabetes observed all countries world. Epidemiological data indicate increases risk cancer, death linked with neoplasms. It still unknown whether this effect antidiabetic or just itself. years there numerous investigations meta-analyzes, based on both comparative cohort studies trying establish relationship between pharmacotherapy mortality due cancer. According their findings, most increase cancer while only few them show antitumor properties. Different action glucose-lowering be responsible for effects. However, published concerning influence were designed some limitations differed approach. review, we discuss association monotherapy polytherapy risk, consider potential