Serologic and immunochemical characterization of the specificity of four monoclonal antibodies to distinct antigenic determinants expressed on subpopulations of human Ia-like antigens.

摘要: Serologic and immunochemical assays showed that the monoclonal antibodies Q2/70, Q2/80, Q5/6, Q5/13 react with human Ia-like antigens. Each antibody recognizes distinct antigenic determinants are different from those defining serologic polymorphism of antigens defined by conventional alloantisera expressed on subpopulations The recognized MoAb Q2/70 all HLA-DR allospecificities tested, whereas reacting Q2/80 Q5/6 not detectable HLA-DR5 HLA-DR7 allospecificities, respectively.