chapter 12 Rna Sequence Complexity in Central Nervous System Development and Plasticity

作者: Lawrence D. Grouse , Bruce K. Schrier , Carol H. Letendre , Phillip G. Nelson

DOI: 10.1016/S0070-2153(08)60163-5

关键词: GeneticsBiologyComplementary DNARNA SequenceNeuroscienceCentral nervous systemTranscription (biology)DNAGene expressionRNACell culture

摘要: Publisher Summary Several lines of research with brain RNA have developed since the initial complexity studies began. This chapter assesses present understanding transcription, reference to hybridization nonrepetitive and complementary DNA. Recent advances in processing its relation are reviewed. The discusses showing effects development, aging, sensory-environmental factors on gene expression. conclusions RNAs clonal cell neural origin presented, implications these data for characterization transcriptional pattern also discussed. Unlike focusing expression individual products or specific physiological properties nerve cells, DNA able define total translational response such key neurobiological events as differentiation synapse formation.

参考文章(47)
Walter Sauerbier, UV Damage at the Transcriptional Level Advances in radiation biology. ,vol. 6, pp. 49- 106 ,(1976) , 10.1016/B978-0-12-035406-1.50007-5
Henry Harris, Nuclear Ribonucleic Acid Progress in Nucleic Acid Research and Molecular Biology. ,vol. 2, pp. 19- 59 ,(1963) , 10.1016/S0079-6603(08)60308-6
Robert B. Church, Gilbert A. Schultz, Differential gene activity in the pre- and postimplantation mammalian embryo. Current Topics in Developmental Biology. ,vol. 8, pp. 179- 202 ,(1974) , 10.1016/S0070-2153(08)60609-2
Torsten N. Wiesel, David H. Hubel, SINGLE-CELL RESPONSES IN STRIATE CORTEX OF KITTENS DEPRIVED OF VISION IN ONE EYE Journal of Neurophysiology. ,vol. 26, pp. 1003- 1017 ,(1963) , 10.1152/JN.1963.26.6.1003
David A. Konkel, Shirley M. Tilghman, Philip Leder, The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites Cell. ,vol. 15, pp. 1125- 1132 ,(1978) , 10.1016/0092-8674(78)90040-5
S. M. Tilghman, D. C. Tiemeier, J. G. Seidman, B. M. Peterlin, M. Sullivan, J. V. Maizel, P. Leder, Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 75, pp. 725- 729 ,(1978) , 10.1073/PNAS.75.2.725
Barbara R. Hough, Michael J. Smith, Roy J. Britten, Eric H. Davidson, Sequence complexity of heterogeneous nuclear RNA in sea urchin embryos Cell. ,vol. 5, pp. 291- 299 ,(1975) , 10.1016/0092-8674(75)90104-X
Armando FELSANI, Francis BERTHELOT, Francois GROS, Bernard CROIZAT, Complexity of Polysomal Polyadenylated RNA in Undifferentiated and Differentiated Neuroblastoma Cells FEBS Journal. ,vol. 92, pp. 569- 577 ,(1978) , 10.1111/J.1432-1033.1978.TB12779.X