Evaluation of red blood cell distribution width in cats with hypertrophic cardiomyopathy

作者: G. Stanzani , R. Cowlam , K. English , D.J. Connolly

DOI: 10.1016/J.JVC.2015.09.001

关键词: Heart failureHematologyRed blood cell distribution widthBiomarker (medicine)Survival analysisCATSPhysical examinationMedicineInternal medicineHypertrophic cardiomyopathyCardiology

摘要: Abstract Background Red blood cell distribution width (RDW) is a measurement of variability in circulating erythrocytes size, and has recently been shown to correlate with prognosis variety human diseases, including acute chronic heart failure. Objectives To determine if RDW differs between healthy controls, cats hypertrophic cardiomyopathy (HCM) without congestive failure (CHF) HCM CHF, evaluate whether values at presentation can provide useful prognostic information HCM. Animals Retrospective single-centre study. Seventy-three diagnosed by echocardiography 30 controls presented veterinary teaching hospital October 2006 April 2013 were included. Physical examination, haematology echocardiographic data obtained on one single visit retrospectively reviewed compared three groups: CHF. Outcome from clinical records or referring veterinarians. Univariable multivariable survival analyses performed. Results was significantly greater CHF the controls. It also associated cardiac mortality univariable analysis, this association remained significant analysis after controlling for effect left atrial ventricular systolic function, haematocrit pro-thrombotic state. Conclusions A higher may be seen an independent predictor death concurrent non-cardiac-related illness.

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