The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer.
作者： Styliani Melissaridou , Emilia Wiechec , Mustafa Magan , Mayur Vilas Jain , Man Ki Chung
DOI: 10.1186/S12935-019-0733-1
关键词: Biology 、 Cell growth 、 Epithelial–mesenchymal transition 、 Stem cell 、 Cell culture 、 Cancer research 、 SOX2 、 Homeobox protein NANOG 、 Head and neck squamous-cell carcinoma 、 Cancer stem cell
摘要: … cells cultured in 3D take on the CSC-like phenotype and our results obtained from 3D culture of HNSCC cells differ significantly from 2D … found between the cell lines regarding changes …
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