A new C30 sterol glycoside from the fresh fruits of Momordica charantia

作者: Peng LIU , Jian-Feng LU , Li-Ping KANG , He-Shui YU , Li-Juan ZHANG

DOI: 10.3724/SP.J.1009.2012.00088

关键词: GlycosideChemistryChemical constituentsBiochemistrySterolSpectral dataChromatographySilica gelMomordica

摘要: AIM: To investigate the chemical constituents from fresh fruits of Momordica charantia L. METHODS: Chemical were isolated and purified by chromatography on silica gel octadecylsilanized (ODS) gel, structures determined spectral data evidence. RESULTS: A new C30 sterol glycoside, named 25-isopropenylchole-5, (6)-ene-3-O--D-glucopyranoside (1), was M. CONCLUSION: Compound 1 is a glycoside.

参考文章(15)
HIKARU OKABE, YUMI MIYAHARA, TATSUO YAMAUCHI, KAZUMOTO MIYAHARA, TOSHIO KAWASAKI, Studies on the constituents of Momordica charantia L. I. Isolation and characterization of momordicosides A and B, glycosides of a pentahydroxy-cucurbitane triterpene. Chemical & Pharmaceutical Bulletin. ,vol. 28, pp. 2753- 2762 ,(1980) , 10.1248/CPB.28.2753
Majekodunmi O. Fatope, Yoshio Takeda, Hiroyasu Yamashita, Hikaru Okabe, Tatsuo Yamauchi, NEW CUCURBITANE TRITERPENOIDS FROM MOMORDICA CHARANTIA Journal of Natural Products. ,vol. 53, pp. 1491- 1497 ,(1990) , 10.1021/NP50072A014
Jian-Chao Chen, Wu-Qing Liu, Lu Lu, Ming-Hua Qiu, Yong-Tang Zheng, Liu-Meng Yang, Xian-Min Zhang, Lin Zhou, Zhong-Rong Li, Kuguacins F-S, cucurbitane triterpenoids from Momordica charantia Phytochemistry. ,vol. 70, pp. 133- 140 ,(2009) , 10.1016/J.PHYTOCHEM.2008.10.011
Anne-Claire Mitaine-Offer, Nicolas Pénez, Tomofumi Miyamoto, Clément Delaude, Jean-François Mirjolet, Olivier Duchamp, Marie-Aleth Lacaille-Dubois, Acylated triterpene saponins from the roots of Securidaca longepedunculata. Phytochemistry. ,vol. 71, pp. 90- 94 ,(2010) , 10.1016/J.PHYTOCHEM.2009.09.022
Xing-Hua Zhu, Hidetsugu Tsumagari, Takehiko Honbu, Tsuyoshi Ikeda, Masateru Ono, Toshihiro Nohara, Peculiar steroidal saponins with opened E-ring from Solanum genera plants Tetrahedron Letters. ,vol. 42, pp. 8043- 8046 ,(2001) , 10.1016/S0040-4039(01)01711-7
Mei Dong, Xi-zhi Feng, Ben-xiang Wang, Li-jun Wu, Takashi Ikejima, Two novel furostanol saponins from the rhizomes of Dioscorea panthaica Prain et Burkill and their cytotoxic activity Tetrahedron. ,vol. 57, pp. 501- 506 ,(2001) , 10.1016/S0040-4020(00)01024-3
Gamarallage V.K Senanayake, Mitsuru Maruyama, Kei Shibuya, Masanobu Sakono, Nobuhiro Fukuda, Toshiro Morishita, Chizuko Yukizaki, Mikio Kawano, Hideaki Ohta, The effects of bitter melon (Momordica charantia) on serum and liver triglyceride levels in rats. Journal of Ethnopharmacology. ,vol. 91, pp. 257- 262 ,(2004) , 10.1016/J.JEP.2003.12.026
Hideaki OHTA, Gamarallage V. K. SENANAYAKE, Mitsuru MARUYAMA, Masanobu SAKONO, Nobuhiro FUKUDA, Toshiro MORISHITA, Chizuko YUKIZAKI, Mikio KAWANO, The Effects of Bitter Melon (Momordica charantia) Extracts on Serum and Liver Lipid Parameters in Hamsters Fed Cholesterol-Free and Cholesterol-Enriched Diets Journal of Nutritional Science and Vitaminology. ,vol. 50, pp. 253- 257 ,(2004) , 10.3177/JNSV.50.253