Dual-spectra ultrasonography: An attenuation-compensating technique for myocardial perfusion analysis
作者： Toshihiko Asanuma , Kjetil Viggen , James B. Seward , Marek Belohlavek
DOI: 10.7863/JUM.2002.21.3.249
关键词: Intensity (physics) 、 Nuclear medicine 、 Perfusion 、 Harmonic 、 Receiver operating characteristic 、 Artery occlusion 、 Sensitivity (electronics) 、 Attenuation 、 Attenuation coefficient 、 Medicine
摘要: Objective. To validate the harmonic-fundamental frequency ratio peak for user-independent differentiation of myocardial perfusion under clinically relevant levels signal attenuation. Methods. Radio data were obtained by using apical long-axis scans in 11 open-chest pigs during continuous infusion a contrast agent after left anterior descending artery occlusion. Silicone pads interposed between transducer and heart to simulate thoracic wall Samples image from perfused nonperfused regions collected; values conventional harmonic gray scale intensity techniques calculated. Results. At each attenuation level, value myocardium was higher than that (P <.0001). The variance these smaller <.0001), with overlap differentiating regions. In receiver operating characteristic curves, this analysis had better diagnostic performance analysis. optimal cutoff value, provided 87% sensitivity 91% specificity; 80% 78% specificity. Conclusions. Harmonic-fundamental differentiated conditions specificity determination attenuated did
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