Brain growth in mice selected for high and low brain weight

作者: John L. Fuller , Helen D. Geils

DOI: 10.1002/DEV.420050404

关键词: EndocrinologyStimulationPeriod (gene)BiologyBrain growthBrain weightNeuroscienceInternal medicineDevelopmental biologyDevelopmental NeuroscienceBehavioral neuroscienceDevelopmental and Educational Psychology

摘要: The growth of brain and body were observed in mice selectively bred for high (H) or low (L) weight as adults. Line H brains tended to be heavier than unselected control (C) at birth throughout the period; line L similar size C birth, but period rapid was shortened. Thus different genetic mechanisms appear involved phenotypic variation upward downward these seem differ timing action. Changes water content indicate that both H- L-lines are maturing more rapidly C-line. Differential temporal patterns may have implications behavioral development, particularly with respect critical periods sensitivity external stimulation.

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