Mutated Src oncogene composition and methods

作者: Timothy J. Yeatman , Rosalyn B. Irby

DOI:

关键词: OncogeneBiochemistryProto-oncogene tyrosine-protein kinase SrcTyrosine kinaseOligonucleotideMolecular biologyTransgeneBiologyMutantRecombinant DNA

摘要: The present invention provides a mutant oligonucleotide composition encoding cellular c-Src tyrosine kinase oncogene. Methods for isolating, expressing and characterizing recombinant Src polypeptide are also provided. further relates to methods utilizing such oligonucleotides, polypeptides, agonists antagonists applications, which relate research, diagnostics, clinical arts. More specifically, this of diagnosing, treating, immunizing, creating transgenic animals based on use Src.

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