Macrophage stimulation in cd47 blockade therapy
作者： Natasja Nielsen Viller , Robert Adam Uger , Gloria Hoi Ying Lin , Lisa Danae Schultz Johnson , Mark Michael Wong
DOI:
关键词: Drug 、 Macrophage 、 Stimulation 、 Blockade 、 Cancer cell 、 Combination therapy 、 CD47 、 Medicine 、 Pharmacology
摘要: Blockade of the CD47/SIRPa pathway depletes cancer cells. This anti-cancer activity is enhanced when macrophage stimulating agents are used in combination with CD47 blockade drug. therapy particularly effective drug SIRPaFc.
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