Arylsulfonyltetrazoles as highly efficient condensing reagents for polynucleotide synthesis

作者: J. Stawinski , T. Hozumi , S. A. Narang

DOI: 10.1139/V76-096

关键词: OligonucleotideOrganic chemistryReagentCombinatorial chemistryPolynucleotideChemistry

摘要: Various arylsulfonyltetrazoles have been investigated to build the phosphotriester bond between appropriately protected oligonucleotides. These reagents found be highly effective with respect time of reaction and yields.