Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats
作者： Adam P. Chambers , Margaret A. Stefater , Hilary E. Wilson-Perez , Lene Jessen , Stephanie Sisley
DOI: 10.1016/J.PHYSBEH.2011.05.026
关键词: Sleeve gastrectomy 、 Blood sugar regulation 、 Diabetes mellitus 、 Energy homeostasis 、 Internal medicine 、 Surgery 、 Gastrectomy 、 Roux-en-Y anastomosis 、 Glucose homeostasis 、 Weight loss 、 Gastroenterology 、 Medicine
摘要: Bariatric surgery is the most efficacious procedure for eliciting weight loss in humans, and many patients undergoing experience significant lessening of their symptoms type-2 diabetes addition to losing weight. We have adapted two bariatric surgical procedures commonly employed humans a rat model begin understand mechanisms underlying improvements energy homeostasis. Young adult male rats received either roux-en-Y gastric bypass (RYGB) or vertical sleeve gastrectomy (VSG) were assessed body weight, food intake parameters glucose homeostasis over 28-week period. Control sham else unoperated. RYGB VSG had comparable beneficial effects relative controls. They ate less lost more they both improved parameters. The intriguing aspect findings that such similar spite quite different rearrangements gastrointestinal system.
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sci-hub.se 参考文章(23)
Edward E. Mason, Chikashi Ito, Gastric Bypass in Obesity Surgical Clinics of North America. ,vol. 47, pp. 1345- 1351 ,(1967) , 10.1016/S0039-6109(16)38384-0
W P T James, WHO recognition of the global obesity epidemic. International Journal of Obesity. ,vol. 32, ,(2008) , 10.1038/IJO.2008.247
Fotis Kalfarentzos, Theodore K. Alexandrides, Stavros N. Karamanakos, Konstantinos Vagenas, Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study Annals of Surgery. ,vol. 247, pp. 401- 407 ,(2008) , 10.1097/SLA.0B013E318156F012
John Melissas, Sofia Koukouraki, John Askoxylakis, Maria Stathaki, Markos Daskalakis, Kostas Perisinakis, Nikos Karkavitsas, Sleeve gastrectomy: a restrictive procedure? Obesity Surgery. ,vol. 17, pp. 57- 62 ,(2007) , 10.1007/S11695-007-9006-5
F. Abbatini, M. Rizzello, G. Casella, G. Alessandri, D. Capoccia, F. Leonetti, N. Basso, Long-term Effects of Laparoscopic Sleeve Gastrectomy, Gastric Bypass, and Adjustable Gastric Banding on Type 2 Diabetes Surgical Endoscopy and Other Interventional Techniques. ,vol. 24, pp. 1005- 1010 ,(2010) , 10.1007/S00464-009-0715-9
Marc Lagacé, Picard Marceau, Simon Marceau, Frédéric-Simon Hould, Martin Potvin, Roch-André Bourque, Simon Biron, Biliopancreatic Diversion with a New Type of Gastrectomy: Some Previous Conclusions Revisited. Obesity Surgery. ,vol. 5, pp. 411- 418 ,(1995) , 10.1381/096089295765557511
Nicholas Stylopoulos, Alison G. Hoppin, Lee M. Kaplan, Roux-en-Y Gastric Bypass Enhances Energy Expenditure and Extends Lifespan in Diet-induced Obese Rats Obesity. ,vol. 17, pp. 1839- 1847 ,(2009) , 10.1038/OBY.2009.207
Ralph Peterli, Bettina Wölnerhanssen, Thomas Peters, Noémie Devaux, Beatrice Kern, Caroline Christoffel-Courtin, Juergen Drewe, Markus von Flüe, Christoph Beglinger, Improvement in glucose metabolism after bariatric surgery : comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy : a prospective randomized trial Annals of Surgery. ,vol. 250, pp. 234- 241 ,(2009) , 10.1097/SLA.0B013E3181AE32E3
Philip R. Schauer, Bartolome Burguera, Sayeed Ikramuddin, Dan Cottam, William Gourash, Giselle Hamad, George M. Eid, Samer Mattar, Ramesh Ramanathan, Emma Barinas-Mitchel, R Harsha Rao, Lewis Kuller, David Kelley, Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. Annals of Surgery. ,vol. 238, pp. 467- 485 ,(2003) , 10.1097/01.SLA.0000089851.41115.1B
Arthur Bohdjalian, Felix B. Langer, Soheila Shakeri-Leidenmühler, Lisa Gfrerer, Bernhard Ludvik, Johannes Zacherl, Gerhard Prager, Sleeve gastrectomy as sole and definitive bariatric procedure: 5-year results for weight loss and ghrelin. Obesity Surgery. ,vol. 20, pp. 535- 540 ,(2010) , 10.1007/S11695-009-0066-6