CRF2 mediates the increased noradrenergic activity in the hypothalamic paraventricular nucleus and the negative state of morphine withdrawal in rats
作者： Javier Navarro-Zaragoza , Cristina Núñez , Jessica Ruiz-Medina , M Luisa Laorden , Olga Valverde
DOI: 10.1111/J.1476-5381.2010.01090.X
关键词: (+)-Naloxone 、 Corticosterone 、 Norepinephrine 、 Opiate 、 Chemistry 、 Morphine 、 Solitary nucleus 、 Tyrosine hydroxylase 、 Stimulation 、 Internal medicine 、 Endocrinology
摘要: … In the present study, AS-30 blocked the morphine withdrawal-increased NA turnover in the PVN, the increased MHPG production and attenuated most of the somatic signs of abstinence…
sci-hub.se 参考文章(44)
M. Luisa Laorden, Cristina Núñez, Pilar Almela, M. Victoria Milanés, Morphine withdrawal-induced c-fos expression in the hypothalamic paraventricular nucleus is dependent on the activation of catecholaminergic neurones. Journal of Neurochemistry. ,vol. 83, pp. 132- 140 ,(2002) , 10.1046/J.1471-4159.2002.01123.X
J. M. Delfs, Y. Zhu, J. P. Druhan, G. Aston-Jones, Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion Nature. ,vol. 403, pp. 430- 434 ,(2000) , 10.1038/35000212
Ana González-Cuello, Maria Luisa Laorden, Maria Victoria Milanés, Gregorio Fuertes, Changes in Catecholaminergic Pathways Innervating Paraventricular Nucleus and Pituitary-Adrenal Axis Response during Morphine Dependence: Implication of α1- and α2-Adrenoceptors Journal of Pharmacology and Experimental Therapeutics. ,vol. 293, pp. 578- 584 ,(2000)
Rachel J. Smith, Gary Aston-Jones, Noradrenergic transmission in the extended amygdala: role in increased drug-seeking and relapse during protracted drug abstinence Brain Structure & Function. ,vol. 213, pp. 43- 61 ,(2008) , 10.1007/S00429-008-0191-3
Catherine A Marcinkiewcz, Melissa M Prado, Shani K Isaac, Alex Marshall, Daria Rylkova, Adrie W Bruijnzeel, Corticotropin-releasing factor within the central nucleus of the amygdala and the nucleus accumbens shell mediates the negative affective state of nicotine withdrawal in rats Neuropsychopharmacology. ,vol. 34, pp. 1743- 1752 ,(2009) , 10.1038/NPP.2008.231
Luis Stinus, Martine Cador, Eric P Zorrilla, George F Koob, Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats. Neuropsychopharmacology. ,vol. 30, pp. 90- 98 ,(2005) , 10.1038/SJ.NPP.1300487
Lisa H. Gold, Luis Stinus, Charles E. Inturrisi, George F. Koob, Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellet implantation in the rat☆ European Journal of Pharmacology. ,vol. 253, pp. 45- 51 ,(1994) , 10.1016/0014-2999(94)90755-2
M. Palkovits, Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Research. ,vol. 59, pp. 449- 450 ,(1973) , 10.1016/0006-8993(73)90290-4
RAFAEL MALDONADO, Participation of noradrenergic pathways in the expression of opiate withdrawal : Biochemical and pharmacological evidence Neuroscience & Biobehavioral Reviews. ,vol. 21, pp. 91- 104 ,(1997) , 10.1016/0149-7634(95)00061-5
George F. Koob, A Role for Brain Stress Systems in Addiction Neuron. ,vol. 59, pp. 11- 34 ,(2008) , 10.1016/J.NEURON.2008.06.012