Interaction of adenine with dichloro-[1-alkyl-2-(naphthylazo)-imidazole]palladium(II) complexes: kinetic and mechanistic studies
作者： Pradip Kumar Ghosh , Harasit Kumar Mandal , Ambikesh Mahapatra
DOI: 10.1007/S11243-010-9379-5
关键词: Palladium 、 Chemical kinetics 、 Catalysis 、 Medicinal chemistry 、 Dissociation (chemistry) 、 Inner sphere electron transfer 、 Reaction rate constant 、 Organometallic chemistry 、 Chemistry 、 Imidazole 、 Stereochemistry
摘要: Interaction of adenine (A) with dichloro-[1-alkyl-2-(α-naphthylazo)imidazole] palladium(II) [Pd(α-NaiR)Cl2], 1 and dichloro-[1-alkyl-2-(β-naphthylazo)imidazole] [Pd(β-NaiR)Cl2], 2 {where R=Me (a), Et (b) or Bz (c)} in MeCN-water (50% v/v) medium to yield [{1-alkyl-2-(α-naphthylazo)imidazole}(adenine)]palladium(II) perchlorates (3a, 3b, 3c) [{1-alkyl-2-(β-naphthylazo)imidazole}(adenine)]palladium(II) (4a, 4b, 4c) was studied. The products were characterized by physico-chemical spectroscopic methods. reaction kinetics second order overall, being first both the Pd(II) complex adenine. effect adding chloride consistent rate-limiting dissociation from complex. Thermodynamic parameters determined temperature variation experiments. second-order rate constant k 2 corroborates experimental Δ‡H° values, while negative values Δ‡S° indicate that proceeds through an associative inner sphere mechanism.
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