Role of Growth Factors in Rotator Cuff Healing

作者: Francesco Oliva , Alessio Giai Via , Nicola Maffulli

DOI: 10.1097/JSA.0B013E3182250C78

关键词: TendonPathologyExtracellular matrixRotator cuff tendinopathyTime courseLesionSurgeryMedicineRotator cuffPhysical Therapy, Sports Therapy and RehabilitationOrthopedics and Sports Medicine

摘要: The histologic lesion underlying overuse rotator cuff tendinopathy is a failed healing response, with haphazard proliferation of tenocytes, disruption tendon cells and collagen fibers, increased noncollagenous extracellular matrix. Recent attention has focused on the biological pathways by which tendons heal, leading to identification several growth factors (GFs) involved in this process. No studies have been published time course various GFs during process vivo, humans. We review what known about these their role healing.

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