Survival advantage from ventricular fibrillation and pulseless electrical activity in women compared to men: the Oregon Sudden Unexpected Death Study

摘要: Studies evaluating a possible survival advantage from sudden cardiac arrest (SCA) in women have produced mixed results possibly due to lack of comprehensive analyses. We hypothesized that race, socioeconomic status (SES), and elements the lifetime clinical history influence gender effects need be incorporated within analyses survival. Cases SCA were identified ongoing, prospective, multiple-source Oregon Sudden Unexpected Death Study (population approximately one million). Subjects included age ≥18 years who underwent attempted resuscitation by EMS providers. Pearson’s chi-square tests independent samples t or analysis variance used for univariate comparisons. evaluated race differences adjusted age, circumstances arrest, disease burden, using logistic regression model predicting A total 1,296 cases had (2002–2007; mean 65 years, male 67%). Women older than men (68 vs. 63 years, p < 0.0001) more likely return spontaneous circulation (41% 33%, p = 0.004). present with pulseless electrical activity (PEA) asystole (p < 0.0001), overall, PEA was common among African Americans (p = 0.04). Higher hospital discharge observed compared presenting ventricular fibrillation/tachycardia (34% 24%, p = 0.02) (10% 3%, p = 0.007). In multivariate adjusting arrhythmia, circumstances, location, SES, survive [odds ratio 1.85; 95% confidence interval (1.12–3.04)]. Despite higher prevalence home, rates PEA, fibrillation activity.