A dual-aptamer-based biosensor for specific detection of breast cancer biomarker HER2 via flower-like nanozymes and DNA nanostructures

作者: Dan Ou , Duanping Sun , Xiangan Lin , Zhixian Liang , Yongsheng Zhong

DOI: 10.1039/C9TB00472F

关键词: NanoprobeDNA–DNA hybridizationDetection limitComplementary DNAAptamerNanotechnologyHorseradish peroxidaseChemistryBiomarker (medicine)Biosensor

摘要: … often easily aggregate and entangle, which blocks the effective binding of aptamers to … to detect proteins. Herein, the TDNs coupled with aptamers provide an orderly sensing interface to …

参考文章(45)
Andrea Ravalli, Carolina Gomes da Rocha, Hideko Yamanaka, Giovanna Marrazza, A label-free electrochemical affisensor for cancer marker detection: The case of HER2 Bioelectrochemistry. ,vol. 106, pp. 268- 275 ,(2015) , 10.1016/J.BIOELECHEM.2015.07.010
Mihaela Skobe, Thomas Hawighorst, David G. Jackson, Remko Prevo, Lauren Janes, Paula Velasco, Lucia Riccardi, Kari Alitalo, Kevin Claffey, Michael Detmar, Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis Nature Medicine. ,vol. 7, pp. 192- 198 ,(2001) , 10.1038/84643
Hongmin Chen, Junhui He, Facile Synthesis of Monodisperse Manganese Oxide Nanostructures and Their Application in Water Treatment Journal of Physical Chemistry C. ,vol. 112, pp. 17540- 17545 ,(2008) , 10.1021/JP806160G
Hao Pei, Na Lu, Yanli Wen, Shiping Song, Yan Liu, Hao Yan, Chunhai Fan, A DNA Nanostructure-based Biomolecular Probe Carrier Platform for Electrochemical Biosensing Advanced Materials. ,vol. 22, pp. 4754- 4758 ,(2010) , 10.1002/ADMA.201002767
Yanyan Yu, Zuanguang Chen, Wensi Jian, Duanping Sun, Beibei Zhang, Xinchun Li, Meicun Yao, Ultrasensitive electrochemical detection of avian influenza A (H7N9) virus DNA based on isothermal exponential amplification coupled with hybridization chain reaction of DNAzyme nanowires Biosensors and Bioelectronics. ,vol. 64, pp. 566- 571 ,(2015) , 10.1016/J.BIOS.2014.09.080
Stéphanie Patris, Pieter De Pauw, Marie Vandeput, Joëlle Huet, Pierre Van Antwerpen, Serge Muyldermans, Jean-Michel Kauffmann, Nanoimmunoassay onto a screen printed electrode for HER2 breast cancer biomarker determination Talanta. ,vol. 130, pp. 164- 170 ,(2014) , 10.1016/J.TALANTA.2014.06.069
Hao Pei, Le Liang, Guangbao Yao, Jiang Li, Qing Huang, Chunhai Fan, Reconfigurable Three‐Dimensional DNA Nanostructures for the Construction of Intracellular Logic Sensors Angewandte Chemie. ,vol. 51, pp. 9020- 9024 ,(2012) , 10.1002/ANIE.201202356
Sherri Rinker, Yonggang Ke, Yan Liu, Rahul Chhabra, Hao Yan, Self-assembled DNA nanostructures for distance-dependent multivalent ligand-protein binding. Nature Nanotechnology. ,vol. 3, pp. 418- 422 ,(2008) , 10.1038/NNANO.2008.164
Takuo Takehana, Kazuyoshi Kunitomo, Koji Kono, Fumiaki Kitahara, Hidehiko Iizuka, Yoshiro Matsumoto, Masayuki A. Fujino, Akishi Ooi, Status of c-erbB-2 in gastric adenocarcinoma: a comparative study of immunohistochemistry, fluorescence in situ hybridization and enzyme-linked immuno-sorbent assay. International Journal of Cancer. ,vol. 98, pp. 833- 837 ,(2002) , 10.1002/IJC.10257