The importance of MUC1 cellular localization in patients with breast carcinoma: an immunohistologic study of 71 patients and review of the literature.

作者: Jennifer J. Rahn , Laith Dabbagh , Manijeh Pasdar , Judith C. Hugh

DOI: 10.1002/1097-0142(20010601)91:11<1973::AID-CNCR1222>3.0.CO;2-A

关键词: ImmunohistochemistryBreast carcinomaMUC1Cellular localizationCarcinomaApical membraneMedicineCancerMetastasisPathology

摘要: … The MUC1 mucin is present on the apical surface of normal secretory epithelia. In breast carcinoma, MUC1 … literature review to better understand the role of MUC1 in breast carcinoma. …

参考文章(43)
Sucharita Adluri, Kenneth O. Lloyd, Govindaswami Ragupathi, Philip O. Livingston, Linda A. Graeber, Friedhelm Helling, Shengle Zhang, Augmenting the Immunogenicity of Synthetic MUC1 Peptide Vaccines in Mice Cancer Research. ,vol. 56, pp. 3315- 3319 ,(1996)
Pramod Pandey, Surender Kharbanda, Donald Kufe, None, Association of the DF3/MUC1 Breast Cancer Antigen with Grb2 and the Sos/Ras Exchange Protein Cancer Research. ,vol. 55, pp. 4000- 4003 ,(1995)
D F Hayes, R Mesa-Tejada, L D Papsidero, G A Croghan, A H Korzun, L Norton, W Wood, J A Strauchen, M Grimes, R B Weiss, Prediction of prognosis in primary breast cancer by detection of a high molecular weight mucin-like antigen using monoclonal antibodies DF3, F36/22, and CU18: a Cancer and Leukemia Group B study. Journal of Clinical Oncology. ,vol. 9, pp. 1113- 1123 ,(1991) , 10.1200/JCO.1991.9.7.1113
L H Regimbald, Reddish, L M Pilarski, B M Longenecker, J C Hugh, G Zimmermann, The breast mucin MUCI as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancer Cancer Research. ,vol. 56, pp. 4244- 4249 ,(1996)
Soo Kie Kim, Govindaswami Ragupathi, Cristina Musselli, Sun-Ju Choi, Yoon Sun Park, Philip O Livingston, Comparison of the effect of different immunological adjuvants on the antibody and T-cell response to immunization with MUC1-KLH and GD3-KLH conjugate cancer vaccines Vaccine. ,vol. 18, pp. 597- 603 ,(1999) , 10.1016/S0264-410X(99)00316-3
A.D. Baildam, A. Howell, Diana M. Barnes, Lesley Turnbull, R.A. Sellwood, The expression of milk fat globule antigens within human mammary tumours: Relationship to steroid hormone receptors and response to endocrine treatment European Journal of Cancer and Clinical Oncology. ,vol. 25, pp. 459- 467 ,(1989) , 10.1016/0277-5379(89)90258-7
MARKKU HELLE, HEIKKI HELIN, JAAKKO ANTONEN, KAI KROHN, Human milk fat globule antigen III D 5, steroid receptors and histopathologic parameters in breast cancer. Apmis. ,vol. 96, pp. 415- 420 ,(1988) , 10.1111/J.1699-0463.1988.TB05324.X
John Samuel, Wladyslaw A. Budzynski, Mark A. Reddish, Lei Ding, Gabrielle L. Zimmermann, Mark J. Krantz, R. Rao Koganty, B. Michael Longenecker, Immunogenicity and antitumor activity of a liposomal MUC1 peptide‐based vaccine International Journal of Cancer. ,vol. 75, pp. 295- 302 ,(1998) , 10.1002/(SICI)1097-0215(19980119)75:2<295::AID-IJC20>3.0.CO;2-B
N Berry, D B Jones, J Smallwood, I Taylor, N Kirkham, J Taylor-Papadimitriou, The prognostic value of the monoclonal antibodies HMFG1 and HMFG2 in breast cancer. British Journal of Cancer. ,vol. 51, pp. 179- 186 ,(1985) , 10.1038/BJC.1985.27