Risk factors for colonization with extended-spectrum beta-lactamase-producing enterobacteriaceae on admission to rehabilitation centres

摘要: Patients newly admitted to rehabilitation centres are at high risk of colonization with multidrug-resistant bacteria because many them have experienced prolonged stays in other healthcare settings and had exposure antibiotics. We conducted a prospective study determine the prevalence factors for extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) this population. Subjects were screened by rectal swab ESBL-PE within 2 days admission. Swabs plated on chromagar ESBL plates presence was verified central laboratory. A multilevel mixed effects model used identify colonization. Of 2873 patients screened, 748 (26.0%) positive ESBL-PE. The variables identified as independently associated were: recent stay an acute-care hospital over weeks (OR = 1.34; 95% CI, 1.12, 1.6), history 2.97; 1.99, 4.43), unconsciousness admission 2.59; 1.55, 4.34), surgery or invasive procedure past year 1.49; 1.2, 1.86) antibiotic treatment month 1.80; 1.45, 2.22). predictive accuracy low (area under ROC curve 0.656). These results indicate that is common upon centres. Some similar those described previously; however, may be specific populations. ability stratify guide infection control empirical strategies settings.