Memory T cell subsets in B cell non-Hodgkin's lymphomas.
作者： Jose I. Diaz , Carlos A. Muro-Cacho , Charles Nicely , Mark G. Edinger , Raymond R. Tubbs
DOI: 10.3109/10428199609051620
关键词: Biopsy 、 Color flow 、 Chemistry 、 Hodgkin s 、 B cell 、 Cytometry 、 Flow cytometry 、 Molecular biology 、 Immunology 、 CD3 、 Memory T cell
摘要: Memory T cells were quantitated by three color flow cytometry in cell suspensions from biopsy specimens of 34 B non-Hodgkin's lymphomas (NHL) and 10 benign lymphoid hyperplasias (BLH). CD3+CD45RO-CD45RA+ (naive), CD3+CD45RO+CDRA- (memory) total CD3+ compared BLH, low grade (LG), intermediate (IG) high (HG) NHL. Mean percentage ± s.e. CD45RO + for LG, IG HG NHL were: 14.7 3.8, 11.2 3.5, 28.9 7.5 45 15, respectively. CD45RA 10.2 2.6, 7.1 2.3, 5.4 1.4 3.5 1.2, 42.5 11, 22.4 7.5, 39.3 10.1 62.7 22.2, progressively increased LG toward while naive simultaneously decreased. Although the differences non-significant, memory significant between (both p. 0100). We previ...
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