Local blood pressure rather than shear stress should be blamed for plaque rupture.

作者: Arnold P.G. Hoeks , Koen D. Reesink , Evelien Hermeling , Robert S. Reneman

DOI: 10.1016/J.JACC.2008.04.071

关键词: Internal medicineFibrous cap% area reductionBlood pressurePlaque ruptureSurgeryMedicineCardiologyShear stressLumen (anatomy)

摘要: A recent article ([1][1]) published in the Journal corroborates hypothesis that shear stress triggers fibrous cap rupture. In 20 patients with considerable lumen narrowing (maximum area reduction of 80 ± 7%), ulcerative plaque rupture preferentially occurred areas locally high wall

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