Remedies for brain ischemic diseases
作者： Nobuo Katsube , Kaneyoshi Honjo , Narito Tateishi
DOI:
关键词: Stereochemistry 、 Tissue plasminogen activator 、 Thrombolytic Agent 、 Alkyl 、 Carbon atom 、 Pharmacology 、 Chemistry 、 Substituent
摘要: Remedies and/or preventives for brain ischemic diseases comprising two active ingredients, namely, an astrocytic function-improving agent, preferably a compound represented by the following general formula (I), and thrombolytic tissue plasminogen activator: (I) wherein R6 represents hydroxy, etc.; (1) n is 1, R11 hydrogen, R5 (alkyl having fluorine atom as substituent of carbon atom)-CH2-; or (2) 0 etc., alkyl, etc. These drugs show synergistic therapeutic effects compared with case where function improving agent are separately administered.
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